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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
27.58
Human Site:
T169
Identified Species:
43.33
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
T169
G
D
I
P
T
F
Y
T
Y
E
E
G
L
S
H
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
Q159
Y
D
V
E
A
H
E
Q
G
Q
G
D
I
P
T
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
L140
F
Y
T
Y
E
E
G
L
S
H
L
T
A
E
G
Dog
Lupus familis
XP_535567
226
24585
L163
F
Y
T
Y
E
G
G
L
S
H
L
T
A
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
T168
G
D
I
P
T
F
Y
T
Y
E
E
G
L
S
H
Rat
Rattus norvegicus
Q04753
236
26074
T168
G
D
I
P
T
F
Y
T
Y
E
E
G
L
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
T179
G
D
L
P
T
F
Y
T
Y
E
E
G
L
S
Q
Chicken
Gallus gallus
XP_423253
238
26615
T170
G
D
I
P
T
F
Y
T
Y
E
E
G
L
S
H
Frog
Xenopus laevis
P54106
241
26428
T173
V
D
V
P
T
F
Y
T
Y
E
E
G
L
S
H
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
T182
G
D
I
P
S
F
Y
T
Y
E
E
G
L
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
A152
T
V
D
T
M
Y
S
A
M
T
T
C
Q
A
L
Honey Bee
Apis mellifera
XP_624081
207
23224
S144
L
H
P
D
P
Q
D
S
F
S
D
A
E
E
D
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
M142
N
P
E
E
D
D
P
M
Y
D
D
E
E
E
E
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
L102
A
M
S
Q
C
Q
A
L
H
P
D
P
D
D
S
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
D168
H
N
W
I
F
S
A
D
Q
L
S
D
E
T
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
6.6
0
0
N.A.
100
100
N.A.
86.6
100
86.6
93.3
N.A.
0
0
6.6
0
P-Site Similarity:
100
26.6
0
0
N.A.
100
100
N.A.
93.3
100
93.3
100
N.A.
13.3
20
20
13.3
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
14
7
0
0
0
7
14
7
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
54
7
7
7
7
7
7
0
7
20
14
7
7
7
% D
% Glu:
0
0
7
14
14
7
7
0
0
47
47
7
20
27
7
% E
% Phe:
14
0
0
0
7
47
0
0
7
0
0
0
0
0
0
% F
% Gly:
40
0
0
0
0
7
14
0
7
0
7
47
0
0
14
% G
% His:
7
7
0
0
0
7
0
0
7
14
0
0
0
0
40
% H
% Ile:
0
0
34
7
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
7
0
0
0
0
20
0
7
14
0
47
0
7
% L
% Met:
0
7
0
0
7
0
0
7
7
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
47
7
0
7
0
0
7
0
7
0
7
0
% P
% Gln:
0
0
0
7
0
14
0
7
7
7
0
0
7
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
7
7
7
7
14
7
7
0
0
47
7
% S
% Thr:
7
0
14
7
40
0
0
47
0
7
7
14
0
7
7
% T
% Val:
7
7
14
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
14
0
14
0
7
47
0
54
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _